Synthetic lipids
NucleoSyn produces and supplies synthetic lipids from milligrams to multi-kilos quantities.
[13C3]-Lipid 5
Packing size
5 mg, 10 mg, 25 mg, bulk
Lipid H (SM102) and Lipid 5 were used for the delivery of mRNA in primates and rapidly cleared from the body resulting in low toxicity. Administration of luciferase mRNA in SM-102-containing lipid nanoparticles induces hepatic luciferase expression in mice. Lipid 5 can be incorporated into LNPs which demonstrated potent delivery of mRNA in primates but also were rapidly cleared from the body resulting in low toxicity.
Nucleosyn provides custom stable isotope lipids to support dedicated projects, such as therapeutic drug monitoring thanks to mass spectrometry.
Aspect
Yellowish oil
Purity
98%
Solubility
DCM, Acetone, Pentane
Molecular weight
713,16
Molecular formula
C4113C3H87NO5
IUPAC
heptadecan-9-yl-8,9,10-13C3 8-((2-hydroxyethyl)(8-(nonyloxy)-8-oxooctyl)amino)octanoate